Lab313ru (DrMefistO) made an awesome IDA plugin that has Sweet mod of gens emulator that lets you debug in IDA pro itself . It also has a very detailed VDP and Sound Debugger IMO similar in many ways to Exodus ( checkbox of all the VDP registers , DMA SRC , DMA low med high etc. as well as graphs for YM2612 sound and status checkboxes for it's attributes ) ROM files loader Z80 sound drivers loader IDA Pro debugger for Sega Mega Drive/Genesis roms and Z80 sound drivers You can set breakpoints on read write to VRAM or VSRAM or VCRAM using his DBG_VDP_VRAM / VSRAM VCRAM sections etc and all kinds of abilities. You can reassemble the rom asm listing from IDA pro using his Batch Scripts as well. You can automatically create include and bin include paths and replace code with other code as well as skip code using markings and then assemble it . What I am describing is just the tip of the iceberg of this tool. Note be sure to go to Tags on Github to get the newest Version. If you dont want to compile it go to releases using newest version. https://github.com/lab313ru/smd_ida_tools2 He also has a Ghidra Plugin for Megadrive Loader. https://github.com/lab313ru/ghidra_sega_ldr IDA Plugin: YM2612 Debugger
The IDA plugin SMD_IDA_Tools 2.9 release now has conditional breakpoints ! https://github.com/lab313ru/smd_ida_tools2/releases/tag/v2.9
SMD_IDA_Tools2 Relase 3.0 has the tile view back! https://github.com/lab313ru/smd_ida_tools2/releases/tag/v3.0